Of Onyx Sierra

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XIENCE Sierra vs. Resolute Onyx

XIENCE Sierra is specifically designed for the treatment of complex patients. Its design engineering, polymer selection and proven clinical safety data make it a leading choice in complex PCI.

Greatest Longitudinal Strength of Any DES1

Best-in-Class Longitudinal Strength for Complex Lesions and Re-Cross1


Displacement of 50 gf Load (mm) Average
XIENCE Sierra

1.2

Orsiro

2.7

Resolute Onyx

5.6

Synergy

11.1

10

6

2

The XIENCE Sierra Stent Design has 3 links per ring that connects peaks of one ring to the valleys of the adjacent ring. This design prevents rings from compressing together and stretching apart (elongating).

Design Drives Conformability

Sierra

Resolute Onyx's fewer weld points may be the cause of worse longitudinal stent deformation. Resolute Onyx also demonstrates more 'clamshells' and 'trainwrecks' when evaluating conformability2.

Treating Side Branches and Large Vessels with XIENCE Sierra Vs. Resolute Onyx

Of Onyx Sierra
XIENCE SIERRARESOLUTE ONYX
Mid-Marker Placement,1 for Precise Deliverability (both stents 3.0 x 18 mm)
Distal Stent to Mid-Marker1(average mm)01.2
Proximal Stent to Mid-Marker1(average mm)01.1
Side Branch Accessibility1,9
Maximum Circular Side Branch Area Diameter
2.04 mm


Maximum Circular Side Branch Area Diameter
1.64 mm

XIENCE Fluoropolymer Vs. Resolute Onyx Polymer

XIENCE has been shown to have superior thromboresistant properties compared to the BioLinx polymer in pre-clinical experiments3.

Test methodology:

  • Human blood was used to collect blood platelets, which were labeled with fluorescent dye to be visualized under confocal microscopy.
  • Devices to be tested were placed in a flow chamber and labeled platelets were circulated at physiological shear rate.

XIENCE Fluoropolymer4

BIOLINX Polymer

XIENCE demonstrates nearly half the stent thrombosis rate of Resolute Onyx and Resolute Integrity at 1 year in multiple trials.

AR Definite/Probable Stent Thrombosis

RESOLUTE Onyx
Core Trial6
RESOLUTE Integrity
All-Comers Trial5

Onyx For Sierra Download

NOTE: Results from clinical trials are not directly comparable. Information provided for educational purposes only.

XIENCE shows a lower TLF rate at 2 years than Resolute Onyx at 1 year

Target Lesion Failure at 1 or 2 Years
RESOLUTE
Onyx6
Synergy7
XIENCE8

NOTE: Results from clinical trials are not directly comparable. Information provided for educational purposes only.

Of Onyx Sierra

TLF in Resolute Onyx Core Trial defined as cardiac death, target vessel-myocardial infarction and target lesion revascularization. All other trials TLF defined as cardiac death, target vessel-myocardial infarction and ischemia driven-target lesion revascularization.

Gmc Sierra Onyx Black Color Code

Onyx is now available for macOS High Sierra. If you’re not familiar with the tool, Onyx is a multifunction utility for macOS that allows you to verify the startup disk and the structure of its system files, to run miscellaneous tasks of system maintenance, to configure some hidden parameters of the Finder, Dock, QuickTime, Safari, Mail, iTunes, login window, Spotlight, and many of Apple’s applications, to delete caches, to remove a certain number of files and folders that may become cumbersome, and more.

Onyx Sierra

Download Onyx here.